Cisternograms in the primate Macaca mulatta.

Normal imaging of cerebrospinal fluid (CSF) flow in the primate Macaca mulatta 99m using Tc labeled human serum albumin shows flow from the basal cisterns over the cerebral cortex in 4 hours. Anatomical correlation of basal cisterns with cisternographic images was demonstrated with latex casts of the normal CSF spaces. Cisternographic images from nonhuman primates with experimental communicating hydrocephalus have entry of radiopharmaceutical into the lateral ventricles and are presented for comparison. Cisternography is a useful technique for evaluating such primate disease models, since normal and pathologic images parallel those obtained in man.